The Allen Institute of Immunology has launched the Human Immune System Explorer (HISE) portal for immunology research.

Initially, the portal performed an information function, supporting the activities of the institute. Today, HISE is an innovative, interactive cell database of the human immune system. Autoimmune diseases and cancer are also objects of research. The portal is developed on the Google cloud platform for easy data exchange, analysis, and interpretation. HISE makes it possible to manage a large volume of data, as well as to monitor the results of clinical studies.

The portal contains PALMO and TEA-seq applications. The first application is a platform for analyzing multidimensional data. The second application is a test that determines epitope and chromatin transcriptomics by sequencing RNA in a single cell.

In 2019, the institute launched a study using genetic sequencing in the collection and analysis of blood and tissue samples from healthy and sick people.

The portal has also shown its functionality in the COVID-19 longitudinal studies. Thus, in today’s realities, HISE has expanded its functionality and now combines the original tasks and COVID-19 studies. The portal continues to evolve towards interactivity with a view to future factual analyses. There are also plans to develop additional applications in the current year.